Sapacitabine

Product Name: Sapacitabine
CAS No.: 151823-14-2
Chemical Name: Sapacitabine
Synonyms: CNDAC;CS-682;CYC 682;CS-2513;Sapacitabine;10G, 50G, 100G, 1KG;Sapacitabine (CS682;Sapacitabine (CYC682);CYC 682; CYC-682; CS-682; CS682; CS 682;1-(2-Deoxy-2-cyano-β-D-arabinofuranosyl)cytosine
CBNumber: CB91261450
Molecular Formula: C26H42N4O5
Formula Weight: 490.64
MOL File: 151823-14-2.mol

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Sapacitabine Property

Melting point:: >177°C (dec.)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 10.04±0.20(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2594
Product name: Sapacitabine
Packaging: 5mg
Price: $78.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2594
Product name: Sapacitabine
Packaging: 25mg
Price: $395
Updated: 2024/03/01

TRC

Product number: S116505
Product name: Sapacitabine
Packaging: 5mg
Price: $120
Updated: 2021/12/16

Usbiological

Product number: 465855
Product name: Sapacitabine
Packaging: 1mg
Price: $360
Updated: 2021/12/16

ChemScene

Product number: CS-0006340
Product name: Sapacitabine
Purity: 98.51%
Packaging: 100mg
Price: $1240
Updated: 2021/12/16

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Sapacitabine Chemical Properties,Usage,Production

Uses

Sapacitabine, it is an orally available nucleoside analog prodrug of CNDAC that acts through a dual mechanism. It has potential use in chemotherapy.

Definition

ChEBI: Sapacitabine is a nucleoside analogue resulting from the formal condensation of the carboxy group of hexadecanoic acid with the amino group of CNDAC. It is the prodrug of CNDAC and is currently in clinical development for the treatment of acute myeloid leukemia (AML). It has a role as an antimetabolite, an antineoplastic agent, a prodrug and a DNA synthesis inhibitor. It is a nucleoside analogue, a nitrile and a secondary carboxamide. It is functionally related to a hexadecanoic acid and a CNDAC.

Biochem/physiol Actions

Sapacitabine is an orally active prodrug of nucleoside analog CNDAC that exhibits potent anti-tumor activity in both blood and solid tumors. CNDAC incorporates into DNA where it causes single-strand breaks (SSBs), which are converted into double strand breaks (DSBs) during S phase.

Sapacitabine Preparation Products And Raw materials

Raw materials

Preparation Products

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Sapacitabine Suppliers

China 46 United States 8 Global 54

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: 16314854226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 9713
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

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View Lastest Price from Sapacitabine manufacturers

Career Henan Chemical Co

Product: Sapacitabine 151823-14-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-24

151823-14-2, SapacitabineRelated Search:

Methylene dithiocyanate Tris(hydroxymethyl)nitromethane CHLOROPHOSPHONAZO III Sodium cyanoborohydride Cyanoacetic acid ETHYL 2-CYANOACRYLATE 4-Ethyl-5-fluoro-6-hydroxypyrimidine 4,6-Dihydroxypyrimidine Sapacitabine Cyano

N-[1-[(2R,3S,4S,5R)-3-cyano-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2- oxo-pyrimidin-4-yl]hexadecanamide

Sapacitabine

1-(2-C-Cyano-2-deoxy-β-D-arabino-pentofuranosyl)cytosine

1-(2-Deoxy-2-cyano-β-D-arabinofuranosyl)cytosine

4-Amino-1-[(3β-cyano-4α-hydroxy-5β-hydroxymethyltetrahydrofuran)-2β-yl]pyrimidin-2(1H)-one

CNDAC

1-(2-cyano-2-deoxy-β-D-arabinofuranosyl)-4-(palMitoylaMino)pyriMidin-2(1H)-one,Sapacitabine

2'-cyano-2'-deoxy-N4-palMitoyl-1-β-D-arabinofuranosyl-cytosine, sapacitabine, CYC682

CYC 682

Sapacitabine (CYC682)

10G, 50G, 100G, 1KG

CS-682

CS-2513

CYC 682; CYC-682; CS-682; CS682; CS 682

Hexadecanamide, N-[1-(2-cyano-2-deoxy-β-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-

Sapacitabine (CS682

151823-14-2

50-27-8

C26H42N4O5